Analysis of spinal cord from fetuses with lethal congenital contracture syndrome (LCCS). LCCS is autosomal recessive, causes death in 32nd gestational week, and involves degeneration of anterior horn motor neurons in spinal cord. Results provide insight into pathways active in motoneuron disease.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Pakkasjärvi N, Gentile M, Saharinen J, Honkanen J et al. Indicative oligodendrocyte dysfunction in spinal cords of human fetuses suffering from a lethal motoneuron disease. J Neurobiol 2005 Dec;65(3):269-81. PMID: 16155903
