Bone morphogenic protein 2 effect on idiopathic pulmonary arterial hypertension
Summary:
Analysis of pulmonary artery smooth muscle cells (PASMC) from patients with idiopathic pulmonary arterial hypertension (IPAH). PASMC treated with 200 nM bone morphogenic protein 2 (BMP-2) for 24 hours. BMP signaling dysfunction has been implicated in IPAH.
GPL8300:
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Citation:
Fantozzi I, Huang W, Zhang J, Zhang S et al. Divergent effects of BMP-2 on gene expression in pulmonary artery smooth muscle cells from normal subjects and patients with idiopathic pulmonary arterial hypertension. Exp Lung Res 2005 Oct;31(8):783-806. PMID: 16368652
