DataSet Record GDS1579: Expression Profiles Data Analysis Tools Sample Subsets
Title: Endotoxin effect on leukocytes: time course (U133 2.0)
Cluster AnalysisGDS1579 Cluster Image
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Summary: Analysis of leukocytes from 6 healthy subjects intravenously administered bacterial endotoxin. Leukocytes examined at various time points up to 6 hours post-infusion. Results provide insight into the molecular mechanisms involved in the propagation and resolution of the inflammatory response.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Calvano SE, Xiao W, Richards DR, Felciano RM et al. A network-based analysis of systemic inflammation in humans. Nature 2005 Oct 13;437(7061):1032-7. PMID: 16136080
  • Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. Multiscale model for the assessment of autonomic dysfunction in human endotoxemia. Physiol Genomics 2010 Jun;42(1):5-19. PMID: 20233835
  • Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. In silico simulation of corticosteroids effect on an NFkB- dependent physicochemical model of systemic inflammation. PLoS One 2009;4(3):e4706. PMID: 19274080
  • Nguyen TT, Calvano SE, Lowry SF, Androulakis IP. An agent-based model of cellular dynamics and circadian variability in human endotoxemia. PLoS One 2013;8(1):e55550. PMID: 23383223
Reference Series: GSE3284 Sample count: 18
Value type: count Series published: 2005/09/14