UV irradiation effect on skin inactivated for tyrosine kinase receptor ErbB2: time course
Summary:
Analysis of the dorsal skin of animals treated with the tyrosine kinase receptor Erbb2 inhibitor AG825 and subsequently exposed to UV radiation. Skin examined 6 and 12 hours after UV irradiation. Results provide insight into the role of Erbb2 in the response to UV and in UV-induced pathologies.
Madson JG, Lynch DT, Tinkum KL, Putta SK et al. Erbb2 regulates inflammation and proliferation in the skin after ultraviolet irradiation. Am J Pathol 2006 Oct;169(4):1402-14. PMID: 17003495
