DataSet Record GDS2172: Expression Profiles Data Analysis Tools Sample Subsets
Title: Pressure overload-induced cardiac hypertrophy effect on interleukin-18 null hearts
Cluster AnalysisGDS2172 Cluster Image
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Summary: Analysis of left ventricles of interleukin (IL)-18 null mutants following surgical transaortic constriction (TAC) to induce cardiac hypertrophy (LVH) by pressure overload. IL-18 is a cardiotropic proinflammatory cytokine. Results provide insight into the role of IL-18 in the hypertrophic response.
Organism: Mus musculus
Platform: GPL339: [MOE430A] Affymetrix Mouse Expression 430A Array
Citation:
  • Colston JT, Boylston WH, Feldman MD, Jenkinson CP et al. Interleukin-18 knockout mice display maladaptive cardiac hypertrophy in response to pressure overload. Biochem Biophys Res Commun 2007 Mar 9;354(2):552-8. PMID: 17250807
Reference Series: GSE5129 Sample count: 4
Value type: count Series published: 2006/07/04