Analysis of embryonic stem cells lacking histone deacetylase 1 (HDAC1). HDACs catalyze the removal of acetyl groups from core histones resulting in chromatin compaction. Results provide insight into the role of HDAC1 in transcriptional regulation.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Zupkovitz G, Tischler J, Posch M, Sadzak I et al. Negative and positive regulation of gene expression by mouse histone deacetylase 1. Mol Cell Biol 2006 Nov;26(21):7913-28. PMID: 16940178
