Analysis of prostate cancer (PC) xenografts collected from male mice up to 14 days after castration. The androgen receptor (AR) plays a pivotal role in the growth and survival of prostate carcinoma. Results provide insight into the role of selective adaptations of the AR pathway in PC progression.
GPL3349:
CMF/NKI produced Human 18K cDNA array, spots 1-19200
Citation:
Hendriksen PJ, Dits NF, Kokame K, Veldhoven A et al. Evolution of the androgen receptor pathway during progression of prostate cancer. Cancer Res 2006 May 15;66(10):5012-20. PMID: 16707422