Analysis of whole blood from individuals with pituitary adenoma predisposition. Pituitary adenomas are common benign neoplasms characterized by oversecretion of growth hormone, leading to acromegaly. Results provide insight into the molecular basis of pituitary adenomas.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Vierimaa O, Georgitsi M, Lehtonen R, Vahteristo P et al. Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science 2006 May 26;312(5777):1228-30. PMID: 16728643