Nicotinamide effect on thrombopoietin-induced megakaryocyte differentiation in vitro
Summary:
Analysis of thrombopoietin-cultured CD34+ cells at various time points up to 5 days following treatment with nicotinamide. Thrombopoietin induces CD34+ cells to differentiate into megakaryocytes. Results provide insight into the effect of nicotinamide on megakaryocyte differentiation.
GPL887:
Agilent-012097 Human 1A Microarray (V2) G4110B (Feature Number version)
Citation:
Giammona LM, Fuhrken PG, Papoutsakis ET, Miller WM. Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes. Br J Haematol 2006 Nov;135(4):554-66. PMID: 17054670
