Histone deacetylase-2 deficiency effect on the embryonic heart
Summary:
Analysis of heart ventricles from histone deacetylase-2 (Hdac2) deficient embryos at embryonic day E17.5. The role of the HDAC family in cardiac myocyte homeostasis is complex. Results provide insight into the role of class I HDAC gene Hdac2 in cardiac development.
Trivedi CM, Luo Y, Yin Z, Zhang M et al. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. Nat Med 2007 Mar;13(3):324-31. PMID: 17322895
