Estrogen-related receptor alpha deficiency effect on the heart
Summary:
Analysis of hearts from mutants lacking estrogen-related receptor alpha (ERRalpha), a nuclear receptor. ERRalpha is a regulator of mitochondrial biogenesis. Results provide insight into the role of ERRalpha in the heart.
Dufour CR, Wilson BJ, Huss JM, Kelly DP et al. Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metab 2007 May;5(5):345-56. PMID: 17488637