Endothelial cell response to chronic activation by tumor necrosis factor
Summary:
Analysis of endothelial cells acutely activated by treatment with soluble tumor necrosis factor (TNF) or chronically activated by expression of an uncleavable form of the transmembrane TNF precursor. Results provide insight into the mechanisms mediating the effect of chronic endothelial activation.
Rajashekhar G, Grow M, Willuweit A, Patterson CE et al. Divergent and convergent effects on gene expression and function in acute versus chronic endothelial activation. Physiol Genomics 2007 Sep 19;31(1):104-13. PMID: 17566077
