X-Box binding protein overexpression effect on breast cancer cell line
Summary:
Analysis of MCF7 breast cancer (BC) cells overexpressing spliced X-box binding protein-1 (XBP1), a transcription factor that participates in the unfolded protein response (UPR). Results provide insight into the role of XBP1 and the UPR in estrogen and antiestrogen responsiveness in breast cancer.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Gomez BP, Riggins RB, Shajahan AN, Klimach U et al. Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines. FASEB J 2007 Dec;21(14):4013-27. PMID: 17660348
