IFN-gamma and IL-1beta effect on thyroid epithelial cells (HG-U133A)
Summary:
Analysis of thyroid epithelial cells (TECs) treated with IFN-gamma, IL-1beta, or both. Fas-mediated apoptosis plays a role in the pathogenesis of autoimmune thyroid diseases. TECs are resistant to Fas-mediated apoptosis, but the resistance is overcome by pretreatment with IFN-gamma and IL-1beta.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Wang SH, Van Antwerp M, Kuick R, Gauger PG et al. Microarray analysis of cytokine activation of apoptosis pathways in the thyroid. Endocrinology 2007 Oct;148(10):4844-52. PMID: 17640998
