Analysis of thoracic aortas (TAs) of Fischer 344/Brown Norway F1 hybrids (F344xBN) at 3 to 28 months of age. Age is a risk factor for vascular disease. The TAs of F344xBN animals exhibit age-related pathologies. Results provide insight into the mechanisms underlying age-mediated vascular pathology.
Miller SJ, Watson WC, Kerr KA, Labarrere CA et al. Development of progressive aortic vasculopathy in a rat model of aging. Am J Physiol Heart Circ Physiol 2007 Nov;293(5):H2634-43. PMID: 17873024
