Oxidative-stress induced neurodegeneration in Harlequin mutant: olfactory epithelium
Summary:
Analysis of olfactory epithelium from Harlequin mutant, a model of oxidative stress (OS)-induced neurodegeneration. OS in the olfactory system is a major factor associated with age-related olfactory impairment. Results provide insight into the molecular basis of OS-associated olfactory aging.
Vaishnav RA, Getchell ML, Huang L, Hersh MA et al. Cellular and molecular characterization of oxidative stress in olfactory epithelium of Harlequin mutant mouse. J Neurosci Res 2008 Jan;86(1):165-82. PMID: 17868149