Staufen1 deletion effect on mRNA abundance in HeLa cells
Summary:
Analysis of HeLa cells depleted of Staufen1 (Stau1). Stau1 is a double-stranded RNA-binding protein that mediates mRNA decay (SMD) and is utilized by mammalian cells to regulate gene expression. Results provide insight into additional mechanisms by which Stau1 may regulate mRNA abundance.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Kim YK, Furic L, Parisien M, Major F et al. Staufen1 regulates diverse classes of mammalian transcripts. EMBO J 2007 Jun 6;26(11):2670-81. PMID: 17510634