DataSet Record GDS3512: Expression Profiles Data Analysis Tools Sample Subsets
Title: Furin deficiency effect on T-cells
Cluster AnalysisGDS3512 Cluster Image
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Summary: Analysis of T-cells lacking the proprotein convertase furin. Proprotein convertases promote the proteolytic maturation of proproteins. Furin is induced in activated T-cells. Results provide insight into the function of furin in T-cells.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citations:
  • Pesu M, Watford WT, Wei L, Xu L et al. T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance. Nature 2008 Sep 11;455(7210):246-50. PMID: 18701887
  • Ortutay Z, Oksanen A, Aittomäki S, Ortutay C et al. Proprotein convertase FURIN regulates T cell receptor-induced transactivation. J Leukoc Biol 2015 Jul;98(1):73-83. PMID: 25926688
Reference Series: GSE11884 Sample count: 4
Value type: count Series published: 2008/06/26