Macrophage migration inhibitory factor depletion effect on kidney cell line
Summary:
Analysis of HEK293 kidney cells depleted for the macrophage migration inhibitory factor (MIF). MIF depletion in HEK293 cells result in G(0)/G(1) cell cycle arrest. Results provide insight into the molecular mechanisms underlying this cell cycle arrest.
Liu L, Ji C, Chen J, Li Y et al. A global genomic view of MIF knockdown-mediated cell cycle arrest. Cell Cycle 2008 Jun 1;7(11):1678-92. PMID: 18469521