Analysis of non-lesional epidermal samples from individuals with atopic dermatitis (AD). AD is characterized by dry eczematous skin lesions, a relapsing and often chronic course, and an intense intractable pruritus. Results provide insight into the molecular pathogenesis of AD.
De Benedetto A, Rafaels NM, McGirt LY, Ivanov AI et al. Tight junction defects in patients with atopic dermatitis. J Allergy Clin Immunol 2011 Mar;127(3):773-86.e1-7. PMID: 21163515