DataSet Record GDS3911: Expression Profiles Data Analysis Tools Sample Subsets
Title: StemRegenin 1 effect on hematopoietic stem cells: dose response
Cluster AnalysisGDS3911 Cluster Image
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Summary: Analysis of hematopoietic stem cells (HSC) treated with StemRegenin 1 (SR1) and LGC006 (a less potent SR1 analog) at 30nM to 1000nM. The use of HSC transplants depends on the ability to expand these cells ex vivo. Results provide insight into molecular basis of SR1-induced ex vivo HSC expansion.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
  • Boitano AE, Wang J, Romeo R, Bouchez LC et al. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science 2010 Sep 10;329(5997):1345-8. PMID: 20688981
Reference Series: GSE28359 Sample count: 8
Value type: transformed count Series published: 2011/04/04