DataSet Record GDS3945: Expression Profiles Data Analysis Tools Sample Subsets
Title: Renal clear cell carcinoma-thyroid hormone receptor mutants: HepG3 cell line
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Summary: Analysis of HepG2 transformants expressing: wildtype thyroid hormone receptors (TRs), hepatocellular carcinoma (HCC)-TR mutants, or renal clear cell carcinoma (RCCC)-TR mutants, in the presence of hormone agonist T3 thyronine. Results provide insight into a unique regulatory repertoire for RCCCs.
Organism: Homo sapiens
Platform: GPL6244: [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
  • Rosen MD, Chan IH, Privalsky ML. Mutant thyroid hormone receptors (TRs) isolated from distinct cancer types display distinct target gene specificities: a unique regulatory repertoire associated with two renal clear cell carcinomas. Mol Endocrinol 2011 Aug;25(8):1311-25. PMID: 21622534
Reference Series: GSE29159 Sample count: 42
Value type: count Series published: 2011/05/10