Estrogen receptor-positive and -negative breast cancer tumors
Summary:
Analysis of primary breast carcinoma tumors from estrogen receptor positive or negative (ER+/-) patients. ER+ tumors tend to metastasize to the bone while ER- tumors tend to induce visceral metastasis. Results provide insight into molecular basis of different metastatic phenotypes in breast cancer.
Julien S, Ivetic A, Grigoriadis A, QiZe D et al. Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers. Cancer Res 2011 Dec 15;71(24):7683-93. PMID: 22025563