Systemic lupus erythematosus and arthritides: synovial biopsies
Summary:
Analysis of synovial biopsies obtained by needle arthroscopy from affected knees of patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), or osteoarthritis (OA). Results provide insight into distinct molecular mechanisms underlying SLE arthritis relative to those of OA and RA.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
Nzeusseu Toukap A, Galant C, Theate I, Maudoux AL et al. Identification of distinct gene expression profiles in the synovium of patients with systemic lupus erythematosus. Arthritis Rheum 2007 May;56(5):1579-88. PMID: 17469140
Lauwerys BR, Hernández-Lobato D, Gramme P, Ducreux J et al. Heterogeneity of synovial molecular patterns in patients with arthritis. PLoS One 2015;10(4):e0122104. PMID: 25927832