Analysis of PBMCs from patients with systemic juvenile idiopathic arthritis (sJIA) or non-sJIA. sJIA patients have significantly increased expansion of immature PBMC subpopulations, including CD34+ cells. Results provide insight into molecular mechanisms underlying sJIA pathogenesis.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Hinze CH, Fall N, Thornton S, Mo JQ et al. Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis. Arthritis Res Ther 2010;12(3):R123. PMID: 20576155