Sex effect on acute coxsackievirus B3-induced myocarditis: heart
Summary:
Analysis of heart from CVB3-infected males during acute myocarditis (day 10 postinfection). Myocarditis and DCM, often caused by viral infections, occur more frequently in men than in women. Results provided insight into molecular basis of progression from acute CVB3 myocarditis to DCM in males.
Coronado MJ, Brandt JE, Kim E, Bucek A et al. Testosterone and interleukin-1β increase cardiac remodeling during coxsackievirus B3 myocarditis via serpin A 3n. Am J Physiol Heart Circ Physiol 2012 Apr 15;302(8):H1726-36. PMID: 22328081
