DataSet Record GDS4374: Expression Profiles Data Analysis Tools Sample Subsets
Title: Entamoeba histolytica infected sigmoid colon
Cluster AnalysisGDS4374 Cluster Image
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Summary: Analysis of colon biopsies from individuals during acute E. histolytica diarrhea (day 1) versus convalescence (day 60) post metronidazole treatment. The E. histolytica pathogen causes diarrhea and colitis. Results provide insight into the molecular mechanisms underlying amebic colitis pathology.
Organism: Homo sapiens
Platform: GPL6244: [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citations:
  • Peterson KM, Guo X, Elkahloun AG, Mondal D et al. The expression of REG 1A and REG 1B is increased during acute amebic colitis. Parasitol Int 2011 Sep;60(3):296-300. PMID: 21586335
  • Marie C, Verkerke HP, Theodorescu D, Petri WA. A whole-genome RNAi screen uncovers a novel role for human potassium channels in cell killing by the parasite Entamoeba histolytica. Sci Rep 2015 Sep 8;5:13613. PMID: 26346926
Reference Series: GSE23750 Sample count: 16
Value type: transformed count Series published: 2011/05/24