External beam radiation therapy effect on prostate cancer patients: peripheral white blood cells
Summary:
Analysis of peripheral blood from men with non-metastatic prostate cancer (PC) on days 1, 7, 14, 21, 42 of external beam radiation therapy (EBRT), and at 30 days post-EBRT. Fatigue is a common side effect of EBRT. Results provide insight into molecular basis of fatigue in men with PC during EBRT.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Saligan LN, Hsiao CP, Wang D, Wang XM et al. Upregulation of α-synuclein during localized radiation therapy signals the association of cancer-related fatigue with the activation of inflammatory and neuroprotective pathways. Brain Behav Immun 2013 Jan;27(1):63-70. PMID: 23022913
