Homeobox transcription factor Dlx5 deficiency effect on embryonic otic vesicle
Summary:
Analysis of otic vesicles from E10 and E10.5 embryos deficient for Dlx5. Dlx5 is a homeobox transcription factor that plays a key role in the development of many organ systems. Results provide insight into the role of Dlx5 in the regulation of early inner ear development.
Sajan SA, Rubenstein JL, Warchol ME, Lovett M. Identification of direct downstream targets of Dlx5 during early inner ear development. Hum Mol Genet 2011 Apr 1;20(7):1262-73. PMID: 21227998