DataSet Record GDS4574: Expression Profiles Data Analysis Tools Sample Subsets
Title: Transforming growth factor-β effect on fibroblasts in the presence of Trypanosoma cruzi conditioned medium
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Summary: Analysis of fibroblasts stimulated with TGF-β in the presence of T. cruzi-conditioned medium (PCM). A soluble factor(s) from T. cruzi inhibits TGF-ß-induced MAP kinase activation. Results provide insight into the ability of secreted parasite molecules to hinder agonist-induced host cell signaling.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
  • Mott GA, Costales JA, Burleigh BA. A soluble factor from Trypanosoma cruzi inhibits transforming growth factor-ß-induced MAP kinase activation and gene expression in dermal fibroblasts. PLoS One 2011;6(9):e23482. PMID: 21931601
Reference Series: GSE16416 Sample count: 12
Value type: count Series published: 2011/09/09