Hippocampus response to acetylcholinesterase inhibitor soman: time course
Summary:
Analysis of hippocampi of Sprauge-Dawley males for up to 168 hours following exposure to the acetylcholinesterase inhibitor soman. Soman is a potent neurotoxicant. Results provide insight into the molecular pathogenesis of soman-induced neurodegeneration.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Dillman JF 3rd, Phillips CS, Kniffin DM, Tompkins CP et al. Gene expression profiling of rat hippocampus following exposure to the acetylcholinesterase inhibitor soman. Chem Res Toxicol 2009 Apr;22(4):633-8. PMID: 19281266