Analysis of NOD-derived, splenic natural killer (NK) cells cultured with or without cytokines interleukin (IL)-12 + IL-18 in the absence of TGF-β, or with both cytokines in the presence of TGF-β. Results provide insight into the impact of TGF-β on NK cells independent of general activation.
Sitrin J, Ring A, Garcia KC, Benoist C et al. Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2. J Exp Med 2013 Jun 3;210(6):1153-65. PMID: 23650440
