DataSet Record GDS4996: Expression Profiles Data Analysis Tools Sample Subsets
Title: Kidney epithelium cell line response to adaptive mutations in Influenza A virus (H3N2) non-structural 1 gene
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Summary: Analysis of M1 cells following infection with H3N2 human influenza isolate A/Hong Kong/1/1968 (HK-wt) or mouse-adapted (MA), recombinant HK NS1 mutants. NS1 protein is a multifunctional virulence factor. Results provide insight into the molecular effects of MA NS1 mutations on host gene expression.
Organism: Mus musculus
Platform: GPL6246: [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Citation:
  • Forbes N, Selman M, Pelchat M, Jia JJ et al. Identification of adaptive mutations in the influenza A virus non-structural 1 gene that increase cytoplasmic localization and differentially regulate host gene expression. PLoS One 2013;8(12):e84673. PMID: 24391972
Reference Series: GSE48217 Sample count: 42
Value type: transformed count Series published: 2013/06/22