Analysis of clear cell renal cell carcinoma (ccRCC) cells treated with A939572, a stearoyl-CoA desaturase 1 (SCD1) inhibitor. SCD1 is overexpressed in ccRCC.Results provide insight into the role of SCD1 in the pathogenesis of ccRCC.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
von Roemeling CA, Marlow LA, Wei JJ, Cooper SJ et al. Stearoyl-CoA desaturase 1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Clin Cancer Res 2013 May 1;19(9):2368-80. PMID: 23633458