DataSet Record GDS5243: Expression Profiles Data Analysis Tools Sample Subsets
Title: Mmp-8 deficient ankle joint response to the induction of arthritis
Cluster AnalysisGDS5243 Cluster Image
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Summary: Analysis of ankle joints of Mmp-8 deficient mutants following treatment with sera from K/BxN mice to induce arthritis. Mmp-8 encodes a metalloproteinase. Results compared to arthritic ankles from wild type animals (GDS5244) and provide insight into the role of Mmp-8 in the pathogenesis of arthritis.
Organism: Mus musculus
Platform: GPL6246: [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Citation:
  • García S, Forteza J, López-Otin C, Gómez-Reino JJ et al. Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model. Arthritis Res Ther 2010;12(6):R224. PMID: 21190566
Reference Series: GSE22971 Sample count: 6
Value type: transformed count Series published: 2010/07/17