Analysis of lung eosinophils of sensitized animals exposed intranasally to ovalbumin to induce eosinophilia. Eosinophilia, higher than normal eosinophil count, is a feature of allergic asthma. Results provide insight into the molecular response of eosinophils to allergen challenge.
Wen T, Mingler MK, Wahl B, Khorki ME et al. Carbonic anhydrase IV is expressed on IL-5-activated murine eosinophils. J Immunol 2014 Jun 15;192(12):5481-9. PMID: 24808371