Non-steroidal anti-inflammatory drug treatment effect on serous ovarian adenocarcinoma cell lines
Summary:
Analysis of ovarian adenocarcinoma cell lines HEY, OVCAR5 and UCI-101 treated 24h with NSAIDs diclofenac or indomethacin (300mM). NSAID drugs associated with a reduced risk of various cancers. Results provide insight into molecular pathways mediating effects of NSAID treatment in ovarian cancer.
Valle BL, D'Souza T, Becker KG, Wood WH 3rd et al. Non-steroidal anti-inflammatory drugs decrease E2F1 expression and inhibit cell growth in ovarian cancer cells. PLoS One 2013;8(4):e61836. PMID: 23637916
