Histone demethylase RBP2 deficiency effect on MDA-MD-231 breast cancer cell line
Summary:
Analysis of MDA-MD-231 breast cancer cell line transfected with siRNAs against RBP2. RBP2 is a histone demethylase (also known as JARID1A and KDM5A) associated with breast cancer metastasis. Results provide insight into roles of RBP2 in breast cancer metastasis.
Cao J, Liu Z, Cheung WK, Zhao M et al. Histone demethylase RBP2 is critical for breast cancer progression and metastasis. Cell Rep 2014 Mar 13;6(5):868-77. PMID: 24582965