E3 ubiquitin ligase PARK2 depletion effect on SF539 glioma cell line
Summary:
Analysis of SF539 glioma cells depleted for PARK2. PARK2 is an E3 ubiquitin ligase. Results provide insight into the role of PARK2 in the coordinate control of cyclins in cell cycle regulation and tumor suppression.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Gong Y, Zack TI, Morris LG, Lin K et al. Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins. Nat Genet 2014 Jun;46(6):588-94. PMID: 24793136
