DataSet Record GDS5645: Expression Profiles Data Analysis Tools Sample Subsets
Title: v-raf murine sarcoma viral oncogene homolog B-mutant thyroid carcinoma tumors
Cluster AnalysisGDS5645 Cluster Image
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Summary: Analysis of papillary thyroid carcinoma (TPOCreER; BrafV600E) and anaplastic thyroid carcinoma (TPOCreER; BrafV600E; p53 -/-) tumors. BRAF and TP53 mutations co-occur often in ATCs, especially those with a precursor PTC. Results provide insight into the molecular basis of PTC to ATC progression.
Organism: Mus musculus
Platform: GPL6246: [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Citation:
  • McFadden DG, Vernon A, Santiago PM, Martinez-McFaline R et al. p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer. Proc Natl Acad Sci U S A 2014 Apr 22;111(16):E1600-9. PMID: 24711431
Reference Series: GSE55933 Sample count: 10
Value type: transformed count Series published: 2014/04/02