Lipopolysaccharide-induced gene expression mediated by Schistosome soluble egg antigen
Summary:
IL10-/- dendritic cells (DC) pulsed for 6 hours with soluble antigen molecules from the eggs of the helminth parasite Schistosoma mansoni (SEA), lipopolysaccharide (LPS), or SEA/LPS to compare changes in LPS-induced gene expression mediated by SEA, and the anti-inflammatory properties of SEA.
Kane CM, Cervi L, Sun J, McKee AS et al. Helminth antigens modulate TLR-initiated dendritic cell activation. J Immunol 2004 Dec 15;173(12):7454-61. PMID: 15585871