6D9H: Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist

PDB ID: 6D9HDownload
MMDB ID: 163631
PDB Deposition Date: 2018/4/29
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.6  Å
Source Organism:
Similar Structures:
Biological Unit for 6D9H: tetrameric; determined by author
Molecular Components in 6D9H
Label Count Molecule
Proteins (4 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-2
(Gene symbol: GNAI2)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Chimera Protein of Muscarinic Acetylcholine Receptor M4 and Adenosine Receptor A1
(Gene symbol: CHRM4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
ADENOSINEADENOSINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303