5W21: Crystal Structure of a 1:1:1 FGF23-FGFR1c-aKlotho Ternary Complex

PDB ID: 5W21Download
MMDB ID: 158519
PDB Deposition Date: 2017/6/5
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 5W21: trimeric; determined by author and by software (PISA)
Molecular Components in 5W21
Label Count Molecule
Proteins (3 molecules)
1
Klotho
(Gene symbol: KL)
Molecule annotation
1
Fibroblast Growth Factor 23
(Gene symbol: FGF23)
Molecule annotation
1
Fibroblast Growth Factor Receptor 1
(Gene symbol: FGFR1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
7
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303