6X7B: BRD4 Bromodomain 1 in complex with multi-action inhibitor SRX3212P

PDB ID: 6X7BDownload
MMDB ID: 190872
PDB Deposition Date: 2020/5/29
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.951  Å
Source Organism:
Similar Structures:
Biological Unit for 6X7B: monomeric; determined by author and by software (PISA)
Molecular Components in 6X7B
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
7-[7-oxo-5-(piperazin-1-yl)-7H-thieno[3,2-b]pyran-3-yl]-N-[(pyridin-3-yl)methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide7-[7-oxo-5-(piperazin-1-yl)-7H-thieno[3,2-b]pyran-3-yl]-N-[(pyridin-3-yl)methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303