1HW4: STRUCTURE OF THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS

PDB ID: 1HW4Download
MMDB ID: 15342
PDB Deposition Date: 2001/1/9
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.06  Å
Source Organism:
Similar Structures:
Biological Unit for 1HW4: dimeric; determined by author and by software (PISA,PQS)
Molecular Components in 1HW4
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
(Gene symbol: TYMS)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
6
SULFATE IONSULFATE ION
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303