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6W25:
Crystal structure of the Melanocortin-4 Receptor (MC4R) in complex with SHU9119
PDB ID:
6W25
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MMDB ID:
187106
PDB Deposition Date:
2020/3/4
Updated in MMDB:
2023/11
Experimental Method:
x-ray diffraction
Resolution:
2.75 Å
Source Organism:
synthetic construct
Similar Structures:
VAST+
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Biological Unit for 6W25: dimeric; determined by software (PISA)
Molecular Components in 6W25
Label
Count
Molecule
Proteins (2 molecules)
A
1
Melanocortin Receptor 4,glga Glycogen Synthase,melanocortin Receptor 4
(Gene symbol:
MC4R
)
B
1
Shu9119
Chemicals and Non-standard biopolymers (9 molecules)
1
1
CALCIUM ION
2
8
OLEIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303