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7SNZ:
Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 6-((2-((4-cyanophenyl)amino)pyrimidin-4-yl)amino)-5,7-dimethylindolizine-2-carbonitrile (JLJ604)
PDB ID:
7SNZ
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MMDB ID:
213273
PDB Deposition Date:
2021/10/28
Updated in MMDB:
2023/10
Experimental Method:
x-ray diffraction
Resolution:
2.368 Å
Source Organism:
Human immunodeficiency virus type 1 BH10
▼
Taxonomy
Molecule
Human immunodeficiency virus type 1 BH10
B
Human immunodeficiency virus 1
A
Similar Structures:
VAST+
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Biological Unit for 7SNZ: dimeric; determined by author and by software (PISA)
Molecular Components in 7SNZ
Label
Count
Molecule
Proteins (2 molecules)
A
1
Reverse Transcriptase P66
B
1
P51 RT
Chemicals and Non-standard biopolymers (8 molecules)
1
1
(4R)-6-{[2-(4-cyanoanilino)pyrimidin-4-yl]amino}-5,7-dimethylindolizine-2-carbonitrile
2
2
SULFATE ION
3
4
MAGNESIUM ION
4
1
1,4-DIAMINOBUTANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303