7SNZ: Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 6-((2-((4-cyanophenyl)amino)pyrimidin-4-yl)amino)-5,7-dimethylindolizine-2-carbonitrile (JLJ604)

PDB ID: 7SNZDownload
MMDB ID: 213273
PDB Deposition Date: 2021/10/28
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.368  Å
Source Organism:
Human immunodeficiency virus type 1 BH10▼
Similar Structures:
Biological Unit for 7SNZ: dimeric; determined by author and by software (PISA)
Molecular Components in 7SNZ
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase P66
Molecule annotation
1
P51 RT
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
(4R)-6-{[2-(4-cyanoanilino)pyrimidin-4-yl]amino}-5,7-dimethylindolizine-2-carbonitrile(4R)-6-{[2-(4-cyanoanilino)pyrimidin-4-yl]amino}-5,7-dimethylindolizine-2-carbonitrile
2
2
SULFATE IONSULFATE ION
3
4
MAGNESIUM IONMAGNESIUM ION
4
1
1,4-DIAMINOBUTANE1,4-DIAMINOBUTANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303