4B99: Crystal Structure of MAPK7 (ERK5) with inhibitor

PDB ID: 4B99Download
MMDB ID: 103038
PDB Deposition Date: 2012/9/3
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 4B99: monomeric; determined by author and by software (PISA)
Molecular Components in 4B99
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 7
(Gene symbol: MAPK7)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
11-cyclopentyl-2-[[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl-phenyl]amino]-5-methyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one11-cyclopentyl-2-[[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl-phenyl]amino]-5-methyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303