4BDK: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)

PDB ID: 4BDKDownload
MMDB ID: 111223
PDB Deposition Date: 2012/10/5
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4BDK: dimeric; determined by author and by software (PISA)
Molecular Components in 4BDK
Label Count Molecule
Proteins (2 molecules)
2
Checkpoint Kinase 2
(Gene symbol: CHEK2)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
N-[(4-methoxyphenyl)methyl]quinoxaline-6-carboxamideN-[(4-methoxyphenyl)methyl]quinoxaline-6-carboxamide
2
2
NITRATE IONNITRATE ION
3
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303