Table 4Characteristics of Included Guidelines

Intended users, target populationRelevant intervention and practice consideredMajor outcomes consideredEvidence collection, selection, and synthesisEvidence quality assessmentRecommendations development and evaluationGuideline validation
Greenberg et al. (2021) 32
Intended users: Surgeons caring for patients scheduled to undergo major elective surgery

Target population: Patients with comorbid conditions (specifically anemia, hyperglycemia, and smoking) undergoing major surgery

Present diagnostic and treatment algorithms for the management of pre-operative anemia including iron supplementation
  • Postoperative hemoglobin and ferritin levels
  • Hospital length of stay days
  • Frequency of transfusion
  • Safety (mortality and adverse events)
A systematic review was undertaken which included multiple database searches (Ovid MEDLINE[R] Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Ovid

MEDLINE[R] Daily and Ovid MEDLINE[R]) from 1946 to time of review

Strength of recommendationa and quality of evidenceb was assessed using GRADERecommendations were developed by 2 reviewersNR

GRADE = Grading of Recommendations Assessment, Development and Evaluation; NR = not reported.

a

Strength of recommendation was assessed using a combination of quality of supporting evidence described as a “balance between desired and undesired effects, how wise the proposed use of resources is, and variability of individual preferences and values.”32 Strength of recommendation was “strong” or “weak”.

b

Quality of evidence was based on how likely further research is to change confidence in the estimate of effect. Classified in 4 levels: “high”, “moderate”, “low”, or “very low”.

Note: This table has not been copy-edited.

From: Intravenous Iron Preparations for Patients Undergoing Elective Surgery: A 2022 Update

Cover of Intravenous Iron Preparations for Patients Undergoing Elective Surgery: A 2022 Update
Intravenous Iron Preparations for Patients Undergoing Elective Surgery: A 2022 Update: Rapid Review [Internet].
Hill S, Severn M; Authors.
Copyright © 2022 Canadian Agency for Drugs and Technologies in Health.

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